Most well know for its berberine content, giving it its bright yellow color and anti-microbial activity. Goldenseal has quite the affinity for the mucous membranes. Very tonic, restorative, antimicrobial, and anti-inflammatory for not just the gut mucosal lining, but also wonderful for sinus infections with much inflammation and congestion. Can be helpful for healing ulcers of the gut as well as the skin. It's quite bitter, and can be useful for stimulating the gastric juices and aiding poor digestion.